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September 2026 Central America & Panama Canal Cruises
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Showing 1 - 10 of 56 Cruises
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Add to Compare
12 Night Central America & Panama Canal Cruise from Fort Lauderdale, FL
Holland America Line Nieuw Amsterdam
Departure Port:
Fort Lauderdale, FL
OCG Class
Premium
Cruises to: ORANJESTAD, ARUBA; CARTAGENA, COLOMBIA; COLON, PANAMA; GATUN LAKE, PANAMA; GEORGETOWN, CAYMAN ISLANDS; FORT LAUDERDALE, FLORIDA, US
Departing
Interior
Oceanview
Balcony
Suite
Oct 18, 2026
$509
$1,109
$1,459
$3,509
Add to Compare
16 Night Central America & Panama Canal Cruise from Los Angeles, CA
Norwegian Cruise Line Norwegian Bliss
Departure Port:
Los Angeles, CA
OCG Class
Mainstream
Cruises to: CABO SAN LUCAS, MEXICO; ACAPULCO, MEXICO; PUERTO QUETZAL, GUATEMALA; PUERTO CALDERA PUNTARENAS, COSTA RICA; PANAMA CITY (PCT), PANAMA; CARTAGENA COLOMBIA; FALMOUTH, JAMAICA
more ...
Departing
Interior
Oceanview
Balcony
Suite
Oct 13, 2026
$1,709
$2,409
$3,259
$3,839
Add to Compare
16 Night Central America & Panama Canal Cruise from Los Angeles, CA
Norwegian Cruise Line Norwegian Joy
Departure Port:
Los Angeles, CA
OCG Class
Mainstream
Cruises to: CABO SAN LUCAS, MEXICO; ACAPULCO, MEXICO; PUERTO QUETZAL, GUATEMALA; PUERTO CALDERA PUNTARENAS, COSTA RICA; PANAMA CITY (PCT), PANAMA; CARTAGENA COLOMBIA; OCHO RIOS, JAMAICA
more ...
Departing
Interior
Oceanview
Balcony
Suite
Oct 7, 2026
$1,279
$1,849
$2,229
$2,499
Add to Compare
16 Night Central America & Panama Canal Cruise from Los Angeles, CA
Princess Cruises Coral Princess
Departure Port:
Los Angeles, CA
OCG Class
Mainstream
Cruises to: Puerto Vallarta; Puerto Chiapas; Puntarenas; Fuerte Amador; Aruba; Fort Lauderdale (Miami)
Departing
Interior
Oceanview
Balcony
Suite
Sep 29, 2026
Contact cruise line for pricing & availability
Add to Compare
16 Night Central America & Panama Canal Cruise from Los Angeles, CA
Princess Cruises Coral Princess
Departure Port:
Los Angeles, CA
OCG Class
Mainstream
Cruises to: PUERTO VALLARTA, MEXICO; HUATULCO, MEXICO; PUERTO CHIAPAS, MEXICO; PUNTARENAS, COSTA RICA; FUERTE AMADOR, PANAMA (FOR PANAMA CITY); ARUBA; FT. LAUDERDALE, FLORIDA
Departing
Interior
Oceanview
Balcony
Suite
Sep 29, 2026
$505
$665
$945
$2,440
Add to Compare
16 Night Central America & Panama Canal Cruise from Los Angeles, CA
Princess Cruises Island Princess
Departure Port:
Los Angeles, CA
OCG Class
Mainstream
Cruises to: PUERTO VALLARTA, MEXICO; HUATULCO, MEXICO; PUERTO CHIAPAS, MEXICO; PUNTARENAS, COSTA RICA; FUERTE AMADOR, PANAMA (FOR PANAMA CITY); ARUBA; FT. LAUDERDALE, FLORIDA
Departing
Interior
Oceanview
Balcony
Suite
Sep 20, 2026
$445
$385
$1,125
$1,810
Add to Compare
16 Night Central America & Panama Canal Cruise from Los Angeles, CA
Princess Cruises Island Princess
Departure Port:
Los Angeles, CA
OCG Class
Mainstream
Cruises to: Puerto Vallarta; Puerto Chiapas; Puntarenas; Fuerte Amador; Aruba; Fort Lauderdale (Miami)
Departing
Interior
Oceanview
Balcony
Suite
Sep 20, 2026
Contact cruise line for pricing & availability
Add to Compare
16 Night Central America & Panama Canal Cruise from Los Angeles, CA
Princess Cruises Star Princess
Departure Port:
Los Angeles, CA
OCG Class
Mainstream
Cruises to: CABO SAN LUCAS, MEXICO; MAZATLAN, MEXICO; FUERTE AMADOR, PANAMA (FOR PANAMA CITY); ARUBA; FT. LAUDERDALE, FLORIDA
Departing
Interior
Oceanview
Balcony
Suite
Oct 4, 2026
$485
$685
$1,685
$4,310
Add to Compare
16 Night Central America & Panama Canal Cruise from San Diego, CA
Holland America Line Eurodam
Departure Port:
San Diego, CA
OCG Class
Premium
Cruises to: CABO SAN LUCAS, MEXICO; ACAPULCO, GUERRERO, MEXICO; HUATULCO, MEXICO; PUERTO CHIAPAS, MEXICO; PUERTO QUETZAL, GUATEMALA; PUNTARENAS (PUERTO CALDERA), COSTA RICA; ORANJESTAD, ARUBA
more ...
Departing
Interior
Oceanview
Balcony
Suite
Oct 8, 2026
$1,179
$1,539
$2,619
$5,039
Add to Compare
16 Night Central America & Panama Canal Cruise from San Diego, CA
Holland America Line Nieuw Amsterdam
Departure Port:
San Diego, CA
OCG Class
Premium
Cruises to: PUERTO VALLARTA, MEXICO; HUATULCO, MEXICO; PUERTO CHIAPAS, MEXICO; PUERTO QUETZAL, GUATEMALA; ACAJUTLA, EL SALVADOR; CARTAGENA, COLOMBIA; FORT LAUDERDALE, FLORIDA, US
Departing
Interior
Oceanview
Balcony
Suite
Oct 2, 2026
$1,089
$1,449
$2,529
$4,859
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